با هم اجراي گام هاي ايفاي نقش را براي تدريس درس درخت (نشانه خ) از نظر مي گذارنيم :
گام اول : تعيين موضوع و نوشتن آن بصورت نمايشنامه؛
در اين گام آموزگار موضوع نمايشنامه را كه اجراي نمايش درخت سخنگو است براي دانش آموزان مشخص مي كند.
آموزگار : بچه ها درس امروز ما درباره درخت و يادگيري نشانه خ است . براي يادگيري اين درس ما با كمك بچه هايي كه از قبل براي اجراي نمايش دواطلب شده اند نمايشي را براي آشنايي با درختان و مراحل رشد آنان ، فوايد درختان و است
گام دوم : فراهم كردن شرايط و وسايل لازم براى اجراى نمايش؛
در اين گام آموزگار شرايط اجراي نمايش و وسايلي كه براي اجراي نمايش نياز است را فراهم مي كند.
آموزگار : بچه ها ما براي اجراي اين نمايش به يك سري و سايل نياز داريم . در ابتدا ما قسمتي از فضاي كلاس را به عنوان يك پارك در نظر مي گيريم و يكي از نيمكت هاي كلاس را در آن جا قرار مي دهيم. سپس براي اجراي نمايش وسايلي نياز داريم كه بايد آن ها را فراهم كنيم مانند ميوه ، برگ ها در اندازه هاي مختلف ، خوراكي هاي مختلف و وسايل ديگر.
گام سوم : تعيين نقش‌هايى كه بايد ايفا شوند؛
در اين گام آموزگار نقش هايي را كه دانش اموزان در اجراي نمايش بايد برعهده بگيرند مشخص مي كند.
چكيده :
Breast cancer is linked to hyperactivation of protein tyrosine kinases (PTKs), and recent studies have unveiled
that selective tyrosine dephosphorylation by protein tyrosine phosphatases (PTPs) of specific substrates,
including PTKs, may activate or inactivate oncogenic pathways in human breast cancer cell growth-related
processes. Here, we review the current knowledge on the involvement of PTPs in breast cancer, as major
regulators of breast cancer therapy-targeted PTKs, such as HER1/EGFR, HER2/Neu, and Src. The functional
interplay between PTKs and PTK-activating or -inactivating PTPs, and its implications in novel breast cancer
therapies based on targeting of specific PTPs, are discussed.
چكيده :
Some thermal decomposition reactions display self-inhibiting behaviour, where the produced gas negatively
influences the reaction progress. Further, a build-up of internal pressure caused by the product gas
may alter the reaction pathway in a way that favours one pathway over others. Two well-known cases of
this kind of reaction are the thermal decomposition of limestone and gibbsite, in which carbon dioxide
and water vapour are the produced gases, respectively. A multi-stage, multi-reaction, shrinking core
model is proposed for the simulation of this type of process. The model emphasises the role of the produced
gas, not only in mass transfer, but also in the reaction kinetics. It includes parallel and series reactions,
allowing for the formation of an intermediate species. The model has been applied to the
conversion of gibbsite to alumina, including the formation of intermediate boehmite. Modelling results
for gibbsite conversion, boehmite formation and its subsequent consumption, as well as alumina formation,
agree well with literature data; the corresponding kinetic parameters are estimated for all reactions.
Significantly, the experimentally-observed plateaux in the particle’s temperature history are predicted by
the model. The role of heating rate and particle size on boehmite formation is also evaluated using the
model, and is in agreement with observation.
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